AN UNBIASED VIEW OF CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most a short while ago, it's been determined that conolidine and the above derivatives act over the atypical chemokine receptor 3 (ACKR3. Expressed in very similar areas as classical opioid receptors, it binds to some wide array of endogenous opioids. Not like most opioid receptors, this receptor acts to be a scavenger and doesn't activate a second